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Feeder-Free Derivation of Human Induced Pluripotent Stem Cells with Messenger RNA

The therapeutic promise of induced pluripotent stem cells (iPSCs) has spurred efforts to circumvent genome alteration when reprogramming somatic cells to pluripotency. Approaches based on episomal DNA, Sendai virus, and messenger RNA (mRNA) can generate “footprint-free” iPSCs with efficiencies equal...

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Detalles Bibliográficos
Autores principales: Warren, Luigi, Ni, Yuhui, Wang, Jiwu, Guo, Xirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442198/
https://www.ncbi.nlm.nih.gov/pubmed/22984641
http://dx.doi.org/10.1038/srep00657