Site-specific DICER and DROSHA RNA products control the DNA damage response

Non-coding RNAs (ncRNAs) are involved in an increasing number of cellular events(1). Some ncRNAs are processed by DICER and DROSHA ribonucleases to give rise to small double-stranded RNAs involved in RNA interference (RNAi)(2). The DNA-damage response (DDR) is a signaling pathway that originates fro...

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Detalles Bibliográficos
Autores principales: Francia, Sofia, Michelini, Flavia, Saxena, Alka, Tang, Dave, de Hoon, Michiel, Anelli, Viviana, Mione, Marina, Carninci, Piero, d’Adda di Fagagna, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442236/
https://www.ncbi.nlm.nih.gov/pubmed/22722852
http://dx.doi.org/10.1038/nature11179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442236/
https://www.ncbi.nlm.nih.gov/pubmed/22722852
http://dx.doi.org/10.1038/nature11179

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