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Dissecting Spatial Knowledge from Spatial Choice by Hippocampal NMDA Receptor Deletion

Hippocampal NMDA receptors (NMDARs) and NMDAR-dependent synaptic plasticity are widely considered as crucial substrates of long-term spatial memory, although their precise role remains uncertain. Here we show that GluN1(ΔDGCA1) mice, lacking NMDARs in all dentate gyrus and dorsal CA1 principal cells...

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Detalles Bibliográficos
Autores principales: Bannerman, David M., Bus, Thorsten, Taylor, Amy, Sanderson, David J., Schwarz, Inna, Jensen, Vidar, Hvalby, Øivind, Rawlins, J. Nicholas P., Seeburg, Peter H., Sprengel, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442238/
https://www.ncbi.nlm.nih.gov/pubmed/22797694
http://dx.doi.org/10.1038/nn.3166