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Wt p53 impairs response to chemotherapy: make lemonade to spare normal cells
As published recently in Cancer Cell, p53 impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer. I discuss that, while treating tumors lacking wt p53, this phenomenon can be exploited to protect normal cells from chemotherapy because all normal cells have wt p53. Also,...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442293/ https://www.ncbi.nlm.nih.gov/pubmed/22802145 |