Reduced Forebrain Serotonin Transmission is Causally Involved in the Development of Compulsive Cocaine Seeking in Rats

Whereas the majority of cocaine users quit as they experience the negative consequences of drug use, some lose control over their drug taking and compulsively seek drugs. We report that 20% of rats compulsively seek cocaine despite intermittent negative outcomes after escalating their cocaine self-a...

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Detalles Bibliográficos
Autores principales: Pelloux, Yann, Dilleen, Ruth, Economidou, Daina, Theobald, David, Everitt, Barry J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442345/
https://www.ncbi.nlm.nih.gov/pubmed/22763621
http://dx.doi.org/10.1038/npp.2012.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442345/
https://www.ncbi.nlm.nih.gov/pubmed/22763621
http://dx.doi.org/10.1038/npp.2012.111

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