Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

Lipid nanoparticles (LNP) are the leading systems for in vivo delivery of small interfering RNA (siRNA) for therapeutic applications. Formulation of LNP siRNA systems requires rapid mixing of solutions containing cationic lipid with solutions containing siRNA. Current formulation procedures employ m...

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Detalles Bibliográficos
Autores principales: Belliveau, Nathan M, Huft, Jens, Lin, Paulo JC, Chen, Sam, Leung, Alex KK, Leaver, Timothy J, Wild, Andre W, Lee, Justin B, Taylor, Robert J, Tam, Ying K, Hansen, Carl L, Cullis, Pieter R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442367/
https://www.ncbi.nlm.nih.gov/pubmed/23344179
http://dx.doi.org/10.1038/mtna.2012.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442367/
https://www.ncbi.nlm.nih.gov/pubmed/23344179
http://dx.doi.org/10.1038/mtna.2012.28

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