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Large G3BP-induced granules trigger eIF2α phosphorylation

Stress granules are large messenger ribonucleoprotein (mRNP) aggregates composed of translation initiation factors and mRNAs that appear when the cell encounters various stressors. Current dogma indicates that stress granules function as inert storage depots for translationally silenced mRNPs until...

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Detalles Bibliográficos
Autores principales: Reineke, Lucas C., Dougherty, Jon D., Pierre, Philippe, Lloyd, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442399/
https://www.ncbi.nlm.nih.gov/pubmed/22833567
http://dx.doi.org/10.1091/mbc.E12-05-0385