Cargando…

Large G3BP-induced granules trigger eIF2α phosphorylation

Stress granules are large messenger ribonucleoprotein (mRNP) aggregates composed of translation initiation factors and mRNAs that appear when the cell encounters various stressors. Current dogma indicates that stress granules function as inert storage depots for translationally silenced mRNPs until...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reineke, Lucas C., Dougherty, Jon D., Pierre, Philippe, Lloyd, Richard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442399/ https://www.ncbi.nlm.nih.gov/pubmed/22833567 http://dx.doi.org/10.1091/mbc.E12-05-0385

Ejemplares similares

4E-BP restrains eIF4E phosphorylation
por: Müller, David, et al.
Publicado: (2013)

The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly
por: Sidrauski, Carmela, et al.
Publicado: (2015)

Metformin blocks MYC protein synthesis in colorectal cancer via mTOR‐4EBP‐eIF4E and MNK1‐eIF4G‐eIF4E signaling
por: Shen, Peng, et al.
Publicado: (2018)

Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation
por: Bogorad, Andrew M., et al.
Publicado: (2017)

Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation
por: Brocard, Michèle, et al.
Publicado: (2020)

Inhibitors of eIF4G1–eIF1 uncover its regulatory role of ER/UPR stress-response genes independent of eIF2α-phosphorylation
por: Sehrawat, Urmila, et al.
Publicado: (2022)

Stress-induced inhibition of translation independently of eIF2α phosphorylation
por: Knutsen, Jon Halvor Jonsrud, et al.
Publicado: (2015)

Mitochondrial Inhibition by Sodium Azide Induces Assembly of eIF2α Phosphorylation-Independent Stress Granules in Mammalian Cells
por: Eiermann, Nina, et al.
Publicado: (2022)

Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1
por: Reineke, Lucas C., et al.
Publicado: (2015)

Phosphorylation of G3BP1-S149 does not influence stress granule assembly
por: Panas, Marc D., et al.
Publicado: (2019)

Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction
por: Wen, Wei, et al.
Publicado: (2020)

Zika virus inhibits eIF2α-dependent stress granule assembly
por: Amorim, Raquel, et al.
Publicado: (2017)

Polycystin-1 inhibits eIF2α phosphorylation and cell apoptosis through a PKR-eIF2α pathway
por: Tang, Yan, et al.
Publicado: (2017)

Reply to “Phosphorylation of G3BP1-S149 does not influence stress granule assembly”
por: Tourrière, Hélène, et al.
Publicado: (2019)

Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy
por: Humeau, Juliette, et al.
Publicado: (2020)

Boric acid induces cytoplasmic stress granule formation, eIF2α phosphorylation, and ATF4 in prostate DU-145 cells
por: Henderson, Kimberly A., et al.
Publicado: (2014)

The Autophagy Protein ATG16L1 Is Required for Sindbis Virus-Induced eIF2α Phosphorylation and Stress Granule Formation
por: Jefferson, Matthew, et al.
Publicado: (2019)

Dissociation of eIF4E-Binding Protein 2 (4E-BP2) from eIF4E Independent of Thr(37)/Thr(46) Phosphorylation in the Ischemic Stress Response
por: Ayuso, María I., et al.
Publicado: (2015)

Structural basis for the inhibition of translation through eIF2α phosphorylation
por: Gordiyenko, Yuliya, et al.
Publicado: (2019)

MARK2 phosphorylates eIF2α in response to proteotoxic stress
por: Lu, Yu-Ning, et al.
Publicado: (2021)

Phosphorylation of Eukaryotic Initiation Factor 4G1 (eIF4G1) at Ser1147 Is Specific for eIF4G1 Bound to eIF4E in Delayed Neuronal Death after Ischemia
por: Martínez-Alonso, Emma, et al.
Publicado: (2022)

eIF4E Phosphorylation in Prostate Cancer()()
por: D'Abronzo, Leandro S., et al.
Publicado: (2018)

Synergistic activation of eIF4A by eIF4B and eIF4G
por: Nielsen, Klaus H., et al.
Publicado: (2011)

Suppression of Hypoxia-Inducible Factor 1α (HIF-1α) by Tirapazamine Is Dependent on eIF2α Phosphorylation Rather Than the mTORC1/4E-BP1 Pathway
por: Zhang, Jun, et al.
Publicado: (2010)

Circadian control of stress granules by oscillating EIF2α
por: Wang, Ruiqi, et al.
Publicado: (2019)

Modulation of p-eIF2α cellular levels and stress granule assembly/disassembly by trehalose
por: Dimasi, Pasquale, et al.
Publicado: (2017)

RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules
por: Kedersha, Nancy L., et al.
Publicado: (1999)

Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK
por: Anderson, Bart R., et al.
Publicado: (2012)

Embryonic Stem Cell Growth Factors Regulate eIF2α Phosphorylation
por: Friend, Kyle, et al.
Publicado: (2015)

Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylation
por: Tsuyama, Taiichi, et al.
Publicado: (2017)

eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation
por: Jennings, Martin D., et al.
Publicado: (2010)

Dendritic eIF4E-binding Protein 1 (eIF4E-BP1) mRNA Is Upregulated by Neuronal Activation
por: Moon, Il Soo, et al.
Publicado: (2012)

Diversion of stress granules and P-bodies during viral infection
por: Reineke, Lucas C., et al.
Publicado: (2013)

Interplay between SERCA, 4E-BP, and eIF4E in the Drosophila heart
por: Santalla, Manuela, et al.
Publicado: (2022)

Relevance of oxidative stress in inhibition of eIF2 alpha phosphorylation and stress granules formation during Usutu virus infection
por: Blázquez, Ana-Belén, et al.
Publicado: (2021)

New Hierarchical Phosphorylation Pathway of the Translational Repressor eIF4E-binding Protein 1 (4E-BP1) in Ischemia-Reperfusion Stress
por: Ayuso, María I., et al.
Publicado: (2010)

FAM69C functions as a kinase for eIF2α and promotes stress granule assembly
por: Wu, Zhongyan, et al.
Publicado: (2023)

Insights into the Role of Yeast eIF2A in IRES-Mediated Translation
por: Reineke, Lucas C., et al.
Publicado: (2011)

The pseudophosphatase MK-STYX inhibits stress granule assembly independently of Ser149 phosphorylation of G3BP-1
por: Barr, Justinn E, et al.
Publicado: (2013)

ER Stress Induces Cell Cycle Arrest at the G2/M Phase Through eIF2α Phosphorylation and GADD45α
por: Lee, Duckgue, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5saomonggh2c040g1q3t7ac7e6