BiP prevents rod opsin aggregation

Mutations in rod opsin—the light-sensitive protein of rod cells—cause retinitis pigmentosa. Many rod opsin mutations lead to protein misfolding, and therefore it is important to understand the role of molecular chaperones in rod opsin biogenesis. We show that BiP (HSPA5) prevents the aggregation of...

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Detalles Bibliográficos
Autores principales: Athanasiou, Dimitra, Kosmaoglou, Maria, Kanuga, Naheed, Novoselov, Sergey S., Paton, Adrienne W., Paton, James C., Chapple, J. Paul, Cheetham, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442401/
https://www.ncbi.nlm.nih.gov/pubmed/22855534
http://dx.doi.org/10.1091/mbc.E12-02-0168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442401/
https://www.ncbi.nlm.nih.gov/pubmed/22855534
http://dx.doi.org/10.1091/mbc.E12-02-0168

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