Cargando…

AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway

The sorting of signaling receptors within the endocytic system is important for appropriate cellular responses. After activation, receptors are trafficked to early endosomes and either recycled or sorted to lysosomes and degraded. Most receptors trafficked to lysosomes are modified with ubiquitin an...

Descripción completa

Detalles Bibliográficos
Autores principales: Dores, Michael R., Paing, May M., Lin, Huilan, Montagne, William A., Marchese, Adriano, Trejo, JoAnn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442409/
https://www.ncbi.nlm.nih.gov/pubmed/22833563
http://dx.doi.org/10.1091/mbc.E12-03-0251