Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis

The endoplasmic reticulum (ER)-Golgi sterol transfer activity of oxysterol-binding protein (OSBP) regulates sphingomyelin (SM) synthesis, as well as post-Golgi cholesterol efflux pathways. The phosphorylation and ER-Golgi localization of OSBP are correlated, suggesting this modification regulates th...

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Detalles Bibliográficos
Autores principales: Goto, Asako, Liu, Xinwei, Robinson, Carolyn-Ann, Ridgway, Neale D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442410/
https://www.ncbi.nlm.nih.gov/pubmed/22875984
http://dx.doi.org/10.1091/mbc.E12-04-0283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442410/
https://www.ncbi.nlm.nih.gov/pubmed/22875984
http://dx.doi.org/10.1091/mbc.E12-04-0283

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