Cargando…

Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis

The endoplasmic reticulum (ER)-Golgi sterol transfer activity of oxysterol-binding protein (OSBP) regulates sphingomyelin (SM) synthesis, as well as post-Golgi cholesterol efflux pathways. The phosphorylation and ER-Golgi localization of OSBP are correlated, suggesting this modification regulates th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goto, Asako, Liu, Xinwei, Robinson, Carolyn-Ann, Ridgway, Neale D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442410/ https://www.ncbi.nlm.nih.gov/pubmed/22875984 http://dx.doi.org/10.1091/mbc.E12-04-0283

Ejemplares similares

Oxysterol Binding Protein-dependent Activation of Sphingomyelin Synthesis in the Golgi Apparatus Requires Phosphatidylinositol 4-Kinase IIα
por: Banerji, Sangeeta, et al.
Publicado: (2010)

Phosphorylation of a serine/proline-rich motif in oxysterol binding protein-related protein 4L (ORP4L) regulates cholesterol and vimentin binding
por: Pietrangelo, Antonietta, et al.
Publicado: (2019)

Regulation of Oxysterol-binding Protein Golgi Localization through Protein Kinase D–mediated Phosphorylation
por: Nhek, Sokha, et al.
Publicado: (2010)

Characterization of the Sterol and Phosphatidylinositol 4-Phosphate Binding Properties of Golgi-Associated OSBP-Related Protein 9 (ORP9)
por: Liu, Xinwei, et al.
Publicado: (2014)

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues
por: Schulz, Timothy A., et al.
Publicado: (2009)

Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes
por: Zhao, Kexin, et al.
Publicado: (2020)

Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein–related proteins and phosphoinositides
por: Raychaudhuri, Sumana, et al.
Publicado: (2006)

Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine
por: Maekawa, Masashi, et al.
Publicado: (2016)

Co-opted Oxysterol-Binding ORP and VAP Proteins Channel Sterols to RNA Virus Replication Sites via Membrane Contact Sites
por: Barajas, Daniel, et al.
Publicado: (2014)

Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding
Publicado: (1992)

Subverting sterols: rerouting an oxysterol-signaling pathway to promote tumor growth
por: York, Autumn G., et al.
Publicado: (2013)

Sterols, Oxysterols, and Accessible Cholesterol: Signalling for Homeostasis, in Immunity and During Development
por: Griffiths, William J., et al.
Publicado: (2021)

Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway
por: Findakly, Sarah, et al.
Publicado: (2020)

ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1
por: Bardwell, A Jane, et al.
Publicado: (2022)

Inhibition of HCV Replication by Oxysterol-Binding Protein-Related Protein 4 (ORP4) through Interaction with HCV NS5B and Alteration of Lipid Droplet Formation
por: Park, In-Woo, et al.
Publicado: (2013)

Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein
por: Strating, Jeroen R.P.M., et al.
Publicado: (2015)

Essential Domains of Oxysterol-Binding Protein Required for Poliovirus Replication
por: Arita, Minetaro
Publicado: (2022)

Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism
por: Yutuc, Eylan, et al.
Publicado: (2020)

Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders()()
por: Griffiths, William J., et al.
Publicado: (2019)

Sterol Regulatory Element-Binding Protein (Sre1) Promotes the Synthesis of Carotenoids and Sterols in Xanthophyllomyces dendrorhous
por: Gutiérrez, María Soledad, et al.
Publicado: (2019)

Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling
por: Nedelcu, Daniel, et al.
Publicado: (2013)

Oxysterol-binding protein-like 2 contributes to the developmental progression of preadipocytes by binding to β-catenin
por: Wang, Tianming, et al.
Publicado: (2021)

Revised sample preparation for the analysis of oxysterols by enzyme-assisted derivatisation for sterol analysis (EADSA)
por: Crick, Peter J., et al.
Publicado: (2015)

The Yeast Oxysterol Binding Protein Kes1 Maintains Sphingolipid Levels
por: LeBlanc, Marissa A., et al.
Publicado: (2013)

Oxysterol binding protein-related protein 8 mediates the cytotoxicity of 25-hydroxycholesterol
por: Li, Jiwei, et al.
Publicado: (2016)

Multisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity
por: Zaytsev, Anatoly V., et al.
Publicado: (2015)

Functions of Oxysterol-Binding Proteins at Membrane Contact Sites and Their Control by Phosphoinositide Metabolism
por: Nakatsu, Fubito, et al.
Publicado: (2021)

A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking
por: Du, Ximing, et al.
Publicado: (2011)

Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth
por: Griffiths, Beatrice, et al.
Publicado: (2013)

Oxysterol-binding protein (OSBP) is required for the perinuclear localization of intra-Golgi v-SNAREs
por: Nishimura, Taki, et al.
Publicado: (2013)

Concerted regulation of npc2 binding to endosomal/lysosomal membranes by bis(monoacylglycero)phosphate and sphingomyelin
por: Enkavi, Giray, et al.
Publicado: (2017)

STARD4 Membrane Interactions and Sterol Binding
por: Iaea, David B., et al.
Publicado: (2015)

Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein
por: Zerbinatti, Celina V, et al.
Publicado: (2008)

Effects of sterol regulatory element-binding protein (SREBP) in chickens
por: Alipour, Fahimeh, et al.
Publicado: (2012)

Role of the Sterol Regulatory Element Binding Protein Pathway in Tumorigenesis
por: Jiang, Tao, et al.
Publicado: (2020)

Multisite phosphorylation code of CDK
por: Örd, Mihkel, et al.
Publicado: (2019)

Insulin‐dependent and ‐independent regulation of sterol regulatory element‐binding protein‐1c
por: Matsuzaka, Takashi, et al.
Publicado: (2013)

Evolutionary History of Oxysterol-Binding Proteins Reveals Complex History of Duplication and Loss in Animals and Fungi
por: Singh, Rohan P., et al.
Publicado: (2023)

Sphingomyelin and GM1 Influence Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes
por: Chaibva, Maxmore, et al.
Publicado: (2018)

ATP-binding cassette protein ABCA7 deficiency impairs sphingomyelin synthesis, cognitive discrimination, and synaptic plasticity in the entorhinal cortex
por: Iqbal, Jahangir, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eq1gmat58vq9v4tdmdqqa71m6m