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Sialylation of N-linked glycans mediates apical delivery of endolyn in MDCK cells via a galectin-9–dependent mechanism

The sialomucin endolyn is implicated in adhesion, migration, and differentiation of various cell types. Along rat kidney tubules, endolyn is variously localized to the apical surface and endosomal/lysosomal compartments. Apical delivery of newly synthesized rat endolyn predominates over direct lysos...

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Detalles Bibliográficos
Autores principales: Mo, Di, Costa, Simone A., Ihrke, Gudrun, Youker, Robert T., Pastor-Soler, Nuria, Hughey, Rebecca P., Weisz, Ora A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442411/
https://www.ncbi.nlm.nih.gov/pubmed/22855528
http://dx.doi.org/10.1091/mbc.E12-04-0329