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ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation
Cells encounter physical cues such as extracellular matrix (ECM) stiffness in a microenvironment replete with biochemical cues. However, the mechanisms by which cells integrate physical and biochemical cues to guide cellular decision making are not well defined. Here we investigate mechanisms by whi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442419/ https://www.ncbi.nlm.nih.gov/pubmed/22833566 http://dx.doi.org/10.1091/mbc.E12-03-0172 |