Hypoxia-inducible Factor-1α (HIF1α) Switches on Transient Receptor Potential Ankyrin Repeat 1 (TRPA1) Gene Expression via a Hypoxia Response Element-like Motif to Modulate Cytokine Release

Transient receptor potential ankyrin repeat 1 (TRPA1) forms calcium (Ca(2+))- and zinc (Zn(2+))-permeable ion channels that sense noxious substances. Despite the biological and clinical importance of TRPA1, there is little knowledge of the mechanisms that lead to transcriptional regulation of TRPA1...

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Detalles Bibliográficos
Autores principales: Hatano, Noriyuki, Itoh, Yuka, Suzuki, Hiroka, Muraki, Yukiko, Hayashi, Hidetoshi, Onozaki, Kikuo, Wood, Ian C., Beech, David J., Muraki, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Membrane Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442528/
https://www.ncbi.nlm.nih.gov/pubmed/22843691
http://dx.doi.org/10.1074/jbc.M112.361139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442528/
https://www.ncbi.nlm.nih.gov/pubmed/22843691
http://dx.doi.org/10.1074/jbc.M112.361139

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