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Lack of response to unaligned chromosomes in mammalian female gametes

Chromosome segregation errors are highly frequent in mammalian female meiosis, and their incidence gradually increases with maternal age. The fate of aneuploid eggs is obviously dependent on the stringency of mechanisms for detecting unattached or repairing incorrectly attached kinetochores. In case...

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Detalles Bibliográficos
Autores principales: Sebestova, Jaroslava, Danylevska, Anna, Novakova, Lucia, Kubelka, Michal, Anger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442912/
https://www.ncbi.nlm.nih.gov/pubmed/22871737
http://dx.doi.org/10.4161/cc.21398