Cargando…

An anti-let-7 sponge decoys and decays endogenous let-7 functions

The let-7 family contains 12 members, which share identical seed regions, suggesting that they may target the same mRNAs. It is essential to develop a means that can regulate the functions of all members. Using a DNA synthesis technique, we have generated an anti-let-7 sponge aiming to modulate the...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Xiangling, Rutnam, Zina Jeyapalan, Jiao, Chunwei, Wei, Duo, Xie, Yizhen, Du, Jun, Zhong, Ling, Yang, Burton B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442920/
https://www.ncbi.nlm.nih.gov/pubmed/22871741
http://dx.doi.org/10.4161/cc.21503