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An anti-let-7 sponge decoys and decays endogenous let-7 functions

The let-7 family contains 12 members, which share identical seed regions, suggesting that they may target the same mRNAs. It is essential to develop a means that can regulate the functions of all members. Using a DNA synthesis technique, we have generated an anti-let-7 sponge aiming to modulate the...

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Detalles Bibliográficos
Autores principales:	Yang, Xiangling, Rutnam, Zina Jeyapalan, Jiao, Chunwei, Wei, Duo, Xie, Yizhen, Du, Jun, Zhong, Ling, Yang, Burton B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442920/ https://www.ncbi.nlm.nih.gov/pubmed/22871741 http://dx.doi.org/10.4161/cc.21503

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