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Whole cell biosynthesis of a functional oligosaccharide, 2′-fucosyllactose, using engineered Escherichia coli

BACKGROUND: 2'-Fucosyllactose (2-FL) is a functional oligosaccharide present in human milk which protects against the infection of enteric pathogens. Because 2-FL can be synthesized through the enzymatic fucosylation of lactose with guanosine 5′-diphosphate (GDP)-l-fucose by α-1,2-fucosyltransf...

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Detalles Bibliográficos
Autores principales: Lee, Won-Heong, Pathanibul, Panchalee, Quarterman, Josh, Jo, Jung-Hyun, Han, Nam Soo, Miller, Michael J, Jin, Yong-Su, Seo, Jin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442965/
https://www.ncbi.nlm.nih.gov/pubmed/22545760
http://dx.doi.org/10.1186/1475-2859-11-48