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Whole cell biosynthesis of a functional oligosaccharide, 2′-fucosyllactose, using engineered Escherichia coli
BACKGROUND: 2'-Fucosyllactose (2-FL) is a functional oligosaccharide present in human milk which protects against the infection of enteric pathogens. Because 2-FL can be synthesized through the enzymatic fucosylation of lactose with guanosine 5′-diphosphate (GDP)-l-fucose by α-1,2-fucosyltransf...
Autores principales: | Lee, Won-Heong, Pathanibul, Panchalee, Quarterman, Josh, Jo, Jung-Hyun, Han, Nam Soo, Miller, Michael J, Jin, Yong-Su, Seo, Jin-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442965/ https://www.ncbi.nlm.nih.gov/pubmed/22545760 http://dx.doi.org/10.1186/1475-2859-11-48 |
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