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ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells

BACKGROUND: The extracellular matrix (ECM) has a key role in facilitating the progression of ovarian cancer and we have shown recently that the secreted ECM protein TGFBI modulates the response of ovarian cancer to paclitaxel-induced cell death. RESULTS: We have determined TGFBI signaling from the e...

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Detalles Bibliográficos
Autores principales: Tumbarello, David A, Temple, Jillian, Brenton, James D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442987/
https://www.ncbi.nlm.nih.gov/pubmed/22640878
http://dx.doi.org/10.1186/1476-4598-11-36