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Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose:methanol mixtures

BACKGROUND: The methylotrophic yeast Pichia pastoris has emerged as one of the most promising yeast hosts for the production of heterologous proteins. Mixed feeds of methanol and a multicarbon source instead of methanol as sole carbon source have been shown to improve product productivities and alle...

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Detalles Bibliográficos
Autores principales: Jordà, Joel, Jouhten, Paula, Cámara, Elena, Maaheimo, Hannu, Albiol, Joan, Ferrer, Pau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443025/
https://www.ncbi.nlm.nih.gov/pubmed/22569166
http://dx.doi.org/10.1186/1475-2859-11-57