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Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose:methanol mixtures
BACKGROUND: The methylotrophic yeast Pichia pastoris has emerged as one of the most promising yeast hosts for the production of heterologous proteins. Mixed feeds of methanol and a multicarbon source instead of methanol as sole carbon source have been shown to improve product productivities and alle...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443025/ https://www.ncbi.nlm.nih.gov/pubmed/22569166 http://dx.doi.org/10.1186/1475-2859-11-57 |