Cargando…
Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose:methanol mixtures
BACKGROUND: The methylotrophic yeast Pichia pastoris has emerged as one of the most promising yeast hosts for the production of heterologous proteins. Mixed feeds of methanol and a multicarbon source instead of methanol as sole carbon source have been shown to improve product productivities and alle...
Autores principales: | Jordà, Joel, Jouhten, Paula, Cámara, Elena, Maaheimo, Hannu, Albiol, Joan, Ferrer, Pau |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443025/ https://www.ncbi.nlm.nih.gov/pubmed/22569166 http://dx.doi.org/10.1186/1475-2859-11-57 |
Ejemplares similares
-
A multi-level study of recombinant Pichia pastoris in different oxygen conditions
por: Baumann, Kristin, et al.
Publicado: (2010) -
Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary (13)C flux analysis
por: Jordà, Joel, et al.
Publicado: (2013) -
Increased dosage of AOX1 promoter-regulated expression cassettes leads to transcription attenuation of the methanol metabolism in Pichia pastoris
por: Cámara, Elena, et al.
Publicado: (2017) -
Quantitative Metabolomics and Instationary (13)C-Metabolic Flux Analysis Reveals Impact of Recombinant Protein Production on Trehalose and Energy Metabolism in Pichia pastoris
por: Jordà, Joel, et al.
Publicado: (2014) -
Macromolecular and elemental composition analysis and extracellular metabolite balances of Pichia pastoris growing at different oxygen levels
por: Carnicer, Marc, et al.
Publicado: (2009)