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Global MicroRNA Profiling of the Mouse Ventricles during Development of Severe Hypertrophic Cardiomyopathy and Heart Failure

MicroRNAs (miRNAs) regulate post-transcriptional gene expression during development and disease. We have determined the miRNA expression levels of early- and end-stage hypertrophic cardiomyopathy (HCM) in a severe, transgenic mouse model of the disease. Five miRNAs were differentially expressed at a...

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Detalles Bibliográficos
Autores principales: Bagnall, Richard D., Tsoutsman, Tatiana, Shephard, Rhian E., Ritchie, William, Semsarian, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443088/
https://www.ncbi.nlm.nih.gov/pubmed/23024758
http://dx.doi.org/10.1371/journal.pone.0044744