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Dynamin 1 Regulates Amyloid Generation through Modulation of BACE-1
BACKGROUND: Several lines of investigation support the notion that endocytosis is crucial for Alzheimer’s disease (AD) pathogenesis. Substantial evidence have already been reported regarding the mechanisms underlying amyloid precursor protein (APP) traffic, but the regulation of beta-site APP-Cleavi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443198/ https://www.ncbi.nlm.nih.gov/pubmed/23024787 http://dx.doi.org/10.1371/journal.pone.0045033 |