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Dynamin 1 Regulates Amyloid Generation through Modulation of BACE-1

BACKGROUND: Several lines of investigation support the notion that endocytosis is crucial for Alzheimer’s disease (AD) pathogenesis. Substantial evidence have already been reported regarding the mechanisms underlying amyloid precursor protein (APP) traffic, but the regulation of beta-site APP-Cleavi...

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Detalles Bibliográficos
Autores principales:	Zhu, Li, Su, Meng, Lucast, Louise, Liu, Lijuan, Netzer, William J., Gandy, Samuel E., Cai, Dongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443198/ https://www.ncbi.nlm.nih.gov/pubmed/23024787 http://dx.doi.org/10.1371/journal.pone.0045033

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