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Prenatal Exposure to TCDD Triggers Significant Modulation of microRNA Expression Profile in the Thymus That Affects Consequent Gene Expression

BACKGROUND: MicroRNAs (miRs) are a class of small RNAs that regulate gene expression. There are over 700 miRs encoded in the mouse genome and modulate most of the cellular pathways and functions by controlling gene expression. However, there is not much known about the pathophysiological role of miR...

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Detalles Bibliográficos
Autores principales: Singh, Narendra P., Singh, Udai P., Guan, Hongbing, Nagarkatti, Prakash, Nagarkatti, Mitzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443208/
https://www.ncbi.nlm.nih.gov/pubmed/23024791
http://dx.doi.org/10.1371/journal.pone.0045054