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Protein Trans-Splicing of an Atypical Split Intein Showing Structural Flexibility and Cross-Reactivity
Inteins catalyze a protein splicing reaction to excise the intein from a precursor protein and join the flanking sequences (exteins) with a peptide bond. In a split intein, the intein fragments (I(N) and I(C)) can reassemble non-covalently to catalyze a trans-splicing reaction that joins the exteins...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443213/ https://www.ncbi.nlm.nih.gov/pubmed/23024818 http://dx.doi.org/10.1371/journal.pone.0045355 |