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Tissue-Specific Strategies of the Very-Long Chain Acyl-CoA Dehydrogenase-Deficient (VLCAD(−/−)) Mouse to Compensate a Defective Fatty Acid β-Oxidation

Very long-chain acyl-CoA dehydrogenase (VLCAD)-deficiency is the most common long-chain fatty acid oxidation disorder presenting with heterogeneous phenotypes. Similar to many patients with VLCADD, VLCAD-deficient mice (VLCAD(−/−)) remain asymptomatic over a long period of time. In order to identify...

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Detalles Bibliográficos
Autores principales: Tucci, Sara, Herebian, Diran, Sturm, Marga, Seibt, Annette, Spiekerkoetter, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443214/
https://www.ncbi.nlm.nih.gov/pubmed/23024820
http://dx.doi.org/10.1371/journal.pone.0045429