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The Histone H4 Lysine 20 Monomethyl Mark, Set by PR-Set7 and Stabilized by L(3)mbt, Is Necessary for Proper Interphase Chromatin Organization

Drosophila PR-Set7 or SET8 is a histone methyltransferase that specifically monomethylates histone H4 lysine 20 (H4K20). L(3)MBT has been identified as a reader of methylated H4K20. It contains several conserved domains including three MBT repeats binding mono- and dimethylated H4K20 peptides. We fi...

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Detalles Bibliográficos
Autores principales: Sakaguchi, Ayako, Joyce, Eric, Aoki, Tsutomu, Schedl, Paul, Steward, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443217/
https://www.ncbi.nlm.nih.gov/pubmed/23024815
http://dx.doi.org/10.1371/journal.pone.0045321