Cargando…

HBsAg Inhibits IFN-α Production in Plasmacytoid Dendritic Cells through TNF-α and IL-10 Induction in Monocytes

Type I Interferon (IFN) is one of the first lines of defense against viral infection. Plasmacytoid dendritic cells (pDCs) are professional IFN-α-producing cells that play an important role in the antiviral immune response. Previous studies have reported that IFN-α production is impaired in chronic h...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Bisheng, Ren, Guangxu, Hu, Yunwen, Wang, Sen, Zhang, Zhanqing, Yuan, Zhenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443230/
https://www.ncbi.nlm.nih.gov/pubmed/23024774
http://dx.doi.org/10.1371/journal.pone.0044900