SIRT1 and c-Myc Promote Liver Tumor Cell Survival and Predict Poor Survival of Human Hepatocellular Carcinomas

The increased expression of SIRT1 has recently been identified in numerous human tumors and a possible correlation with c-Myc oncogene has been proposed. However, it remains unclear whether SIRT1 functions as an oncogene or tumor suppressor. We sought to elucidate the role of SIRT1 in liver cancer u...

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Detalles Bibliográficos
Autores principales: Jang, Kyu Yun, Noh, Sang Jae, Lehwald, Nadja, Tao, Guo-Zhong, Bellovin, David I., Park, Ho Sung, Moon, Woo Sung, Felsher, Dean W., Sylvester, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443243/
https://www.ncbi.nlm.nih.gov/pubmed/23024800
http://dx.doi.org/10.1371/journal.pone.0045119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443243/
https://www.ncbi.nlm.nih.gov/pubmed/23024800
http://dx.doi.org/10.1371/journal.pone.0045119

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