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Elevated Serum Ferritin Is Associated with Reduced Survival in Amyotrophic Lateral Sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder caused by the loss of motor neurons. Its etiology remains unknown, but several hypothesis have been raised to explain motor neuron death, including oxidative stress. Dysregulation of cellular iron metabolism can lead to...

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Detalles Bibliográficos
Autores principales: Nadjar, Yann, Gordon, Paul, Corcia, Philippe, Bensimon, Gilbert, Pieroni, Laurence, Meininger, Vincent, Salachas, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443244/
https://www.ncbi.nlm.nih.gov/pubmed/23024788
http://dx.doi.org/10.1371/journal.pone.0045034