hESC-Derived Cardiomyocytes Electrically Couple and Suppress Arrhythmias in Injured Hearts

Transplantation studies in mice and rats have shown that human embryonic stem cell-derived cardiomyocytes (hESC-CMs) can improve the function of infarcted hearts(1–3), but two critical issues related to their electrophysiological behavior in vivo remain unresolved. First, the risk of arrhythmias fol...

Descripción completa

Detalles Bibliográficos
Autores principales: Shiba, Yuji, Fernandes, Sarah, Zhu, Wei-Zhong, Filice, Dominic, Muskheli, Veronica, Kim, Jonathan, Palpant, Nathan J., Gantz, Jay, Moyes, Kara White, Reinecke, Hans, Van Biber, Benjamin, Dardas, Todd, Mignone, John L., Izawa, Atsushi, Hanna, Ramy, Viswanathan, Mohan, Gold, Joseph D., Kotlikoff, Michael I., Sarvazyan, Narine, Kay, Matthew W., Murry, Charles E., Laflamme, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443324/
https://www.ncbi.nlm.nih.gov/pubmed/22864415
http://dx.doi.org/10.1038/nature11317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443324/
https://www.ncbi.nlm.nih.gov/pubmed/22864415
http://dx.doi.org/10.1038/nature11317

Ejemplares similares