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Attenuation of indomethacin-induced gastric mucosal injury by prophylactic administration of sake yeast-derived thioredoxin

BACKGROUND: Indomethacin is one of the group of nonsteroidal anti-inflammatory drugs, which often cause gastric mucosal injury as a side effect. Infiltration and activation of inflammatory cells, production of proinflammatory cytokines and chemokines, generation of reactive oxygen species, and activ...

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Detalles Bibliográficos
Autores principales: Nakajima, Atsushi, Fukui, Toshiro, Takahashi, Yu, Kishimoto, Masanobu, Yamashina, Masao, Nakayama, Shinji, Sakaguchi, Yutaku, Yoshida, Katsunori, Uchida, Kazushige, Nishio, Akiyoshi, Yodoi, Junji, Okazaki, Kazuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443347/
https://www.ncbi.nlm.nih.gov/pubmed/22402774
http://dx.doi.org/10.1007/s00535-012-0564-5