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Flux variability scanning based on enforced objective flux for identifying gene amplification targets

BACKGROUND: In order to reduce time and efforts to develop microbial strains with better capability of producing desired bioproducts, genome-scale metabolic simulations have proven useful in identifying gene knockout and amplification targets. Constraints-based flux analysis has successfully been em...

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Detalles Bibliográficos
Autores principales: Park, Jong Myoung, Park, Hye Min, Kim, Won Jun, Kim, Hyun Uk, Kim, Tae Yong, Lee, Sang Yup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443430/
https://www.ncbi.nlm.nih.gov/pubmed/22909053
http://dx.doi.org/10.1186/1752-0509-6-106