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Flux variability scanning based on enforced objective flux for identifying gene amplification targets
BACKGROUND: In order to reduce time and efforts to develop microbial strains with better capability of producing desired bioproducts, genome-scale metabolic simulations have proven useful in identifying gene knockout and amplification targets. Constraints-based flux analysis has successfully been em...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443430/ https://www.ncbi.nlm.nih.gov/pubmed/22909053 http://dx.doi.org/10.1186/1752-0509-6-106 |