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RNA interference-mediated silencing of eukaryotic translation initiation factor 3, subunit B (EIF3B) gene expression inhibits proliferation of colon cancer cells

BACKGROUND: A key factor underlying the control of the cellular growth, size and proliferation involves the regulation of the total protein synthesis. Most often, the initial stages of mRNA translation are rate limiting, which involves a group of eukaryotic translation initiation factors (EIFs). Res...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Chen, Jinxian, Sun, Jianhua, Cui, Zhe, Wu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443437/
https://www.ncbi.nlm.nih.gov/pubmed/22734884
http://dx.doi.org/10.1186/1477-7819-10-119