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Vitiligo inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8

Vitiligo is characterized by depigmented skin patches due to loss of epidermal melanocytes. Oxidative stress may play a role in vitiligo onset, while autoimmunity contributes to disease progression. In this study we sought to identify mechanisms that link disease triggers and spreading of lesions. A...

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Detalles Bibliográficos
Autores principales: Toosi, Siavash, Orlow, Seth J., Manga, Prashiela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443495/
https://www.ncbi.nlm.nih.gov/pubmed/22696056
http://dx.doi.org/10.1038/jid.2012.181