YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14

The Yes-associated protein (YAP) is a transcriptional factor involved in tissue development and tumorigenesis. Although YAP has been recognized as a key element of the Hippo signaling pathway, the mechanisms that regulate YAP activities remain to be fully characterized. In this study, we demonstrate...

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Detalles Bibliográficos
Autores principales: Huang, Jen-Ming, Nagatomo, Izumi, Suzuki, Emi, Mizuno, Takako, Kumagai, Toru, Berezov, Alan, Zhang, Hongtao, Karlan, Beth, Greene, Mark I., Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443515/
https://www.ncbi.nlm.nih.gov/pubmed/22689061
http://dx.doi.org/10.1038/onc.2012.231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443515/
https://www.ncbi.nlm.nih.gov/pubmed/22689061
http://dx.doi.org/10.1038/onc.2012.231

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