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Centrality-based pathway enrichment: a systematic approach for finding significant pathways dominated by key genes

BACKGROUND: Biological pathways are important for understanding biological mechanisms. Thus, finding important pathways that underlie biological problems helps researchers to focus on the most relevant sets of genes. Pathways resemble networks with complicated structures, but most of the existing pa...

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Detalles Bibliográficos
Autores principales: Gu, Zuguang, Liu, Jialin, Cao, Kunming, Zhang, Junfeng, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443660/
https://www.ncbi.nlm.nih.gov/pubmed/22672776
http://dx.doi.org/10.1186/1752-0509-6-56