Archaeal proteins Nop10 and Gar1 increase the catalytic activity of Cbf5 in pseudouridylating tRNA

Cbf5 is a pseudouridine synthase that usually acts in a guide RNA-dependent manner as part of H/ACA small ribonucleoproteins; however archaeal Cbf5 can also act independently of guide RNA in modifying uridine 55 in tRNA. This guide-independent activity of Cbf5 is enhanced by proteins Nop10 and Gar1...

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Detalles Bibliográficos
Autores principales: Kamalampeta, Rajashekhar, Kothe, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443816/
https://www.ncbi.nlm.nih.gov/pubmed/22993689
http://dx.doi.org/10.1038/srep00663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443816/
https://www.ncbi.nlm.nih.gov/pubmed/22993689
http://dx.doi.org/10.1038/srep00663

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