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KIR2DL5: An Orphan Inhibitory Receptor Displaying Complex Patterns of Polymorphism and Expression

A recently developed anti-KIR2DL5 (CD158f) antibody has demonstrated KIR2DL5 expression on the surface of NK and T lymphocytes, making it the last functional KIR identified in the human genome. KIR2DL5 belongs to an ancestral lineage of KIR with Ig-like domains of the D0-D2 type, of which KIR2DL4, a...

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Detalles Bibliográficos
Autores principales: Cisneros, Elisa, Moraru, Manuela, Gómez-Lozano, Natalia, López-Botet, Miguel, Vilches, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443818/
https://www.ncbi.nlm.nih.gov/pubmed/23060877
http://dx.doi.org/10.3389/fimmu.2012.00289