Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53

Poly-ADP ribose polymerase (PARP) inhibitors have shown promise in the treatment of human malignancies characterized by deficiencies in the DNA damage repair proteins BRCA1 and BRCA2 and preclinical studies have demonstrated the potential effectiveness of PARP inhibitors in targeting ataxia-telangie...

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Detalles Bibliográficos
Autores principales: Williamson, Chris T, Kubota, Eiji, Hamill, Jeffrey D, Klimowicz, Alexander, Ye, Ruiqiong, Muzik, Huong, Dean, Michelle, Tu, LiRen, Gilley, David, Magliocco, Anthony M, McKay, Bruce C, Bebb, D Gwyn, Lees-Miller, Susan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443945/
https://www.ncbi.nlm.nih.gov/pubmed/22416035
http://dx.doi.org/10.1002/emmm.201200229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443945/
https://www.ncbi.nlm.nih.gov/pubmed/22416035
http://dx.doi.org/10.1002/emmm.201200229

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