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Knockdown of glucose-regulated protein 78 decreases the invasion, metalloproteinase expression and ECM degradation in hepatocellular carcinoma cells

BACKGROUND: We have reported previously that overexpression of glucose-regulated protein 78 (GRP78) promotes the invasion of hepatocellular carcinoma. However, whether GRP78 knockdown affects the extracellular matrix degradation has not been elucidated. Here we are going to determine whether GRP78 k...

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Detalles Bibliográficos
Autores principales: Li, Hongdan, Song, Huijuan, Luo, Junsheng, Liang, Jia, Zhao, Song, Su, Rongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444337/
https://www.ncbi.nlm.nih.gov/pubmed/22546345
http://dx.doi.org/10.1186/1756-9966-31-39