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Straightforward thiol-mediated protein labelling with DTPA: Synthesis of a highly active (111)In-annexin A5-DTPA tracer

BACKGROUND: Annexin A5 (anxA5) has been found useful for molecular imaging of apoptosis and other biological processes. METHODS: Here, we report an optimised two-step synthesis of annexin A5-diethylene triamine pentaacetic acid (DTPA) (anxA5-DTPA) for positron emission tomography (PET) and single-ph...

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Detalles Bibliográficos
Autores principales: Kratz, Harald, Haeckel, Akvile, Michel, Roger, Schönzart, Lena, Hanisch, Uli, Hamm, Bernd, Schellenberger, Eyk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444359/
https://www.ncbi.nlm.nih.gov/pubmed/22541756
http://dx.doi.org/10.1186/2191-219X-2-17