Reduced BMP Signaling Results in Hindlimb Fusion with Lethal Pelvic/Urogenital Organ Aplasia: A New Mouse Model of Sirenomelia

Sirenomelia, also known as mermaid syndrome, is a developmental malformation of the caudal body characterized by leg fusion and associated anomalies of pelvic/urogenital organs including bladder, kidney, rectum and external genitalia. Most affected infants are stillborn, and the few born alive rarel...

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Detalles Bibliográficos
Autores principales: Suzuki, Kentaro, Adachi, Yasuha, Numata, Tomokazu, Nakada, Shoko, Yanagita, Motoko, Nakagata, Naomi, Evans, Sylvia M., Graf, Daniel, Economides, Aris, Haraguchi, Ryuma, Moon, Anne M., Yamada, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444444/
https://www.ncbi.nlm.nih.gov/pubmed/23028455
http://dx.doi.org/10.1371/journal.pone.0043453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444444/
https://www.ncbi.nlm.nih.gov/pubmed/23028455
http://dx.doi.org/10.1371/journal.pone.0043453

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