Human Lung Cancer Cells Grown in an Ex Vivo 3D Lung Model Produce Matrix Metalloproteinases Not Produced in 2D Culture

We compared the growth of human lung cancer cells in an ex vivo three-dimensional (3D) lung model and 2D culture to determine which better mimics lung cancer growth in patients. A549 cells were grown in an ex vivo 3D lung model and in 2D culture for 15 days. We measured the size and formation of tum...

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Detalles Bibliográficos
Autores principales: Mishra, Dhruva K., Sakamoto, Jason H., Thrall, Michael J., Baird, Brandi N., Blackmon, Shanda H., Ferrari, Mauro, Kurie, Jonathan M., Kim, Min P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444466/
https://www.ncbi.nlm.nih.gov/pubmed/23028922
http://dx.doi.org/10.1371/journal.pone.0045308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444466/
https://www.ncbi.nlm.nih.gov/pubmed/23028922
http://dx.doi.org/10.1371/journal.pone.0045308

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