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Mitochondrial Genomic Analysis of Late Onset Alzheimer’s Disease Reveals Protective Haplogroups H6A1A/H6A1B: The Cache County Study on Memory in Aging

BACKGROUND: Alzheimer’s disease (AD) is the most common cause of dementia and AD risk clusters within families. Part of the familial aggregation of AD is accounted for by excess maternal vs. paternal inheritance, a pattern consistent with mitochondrial inheritance. The role of specific mitochondrial...

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Detalles Bibliográficos
Autores principales: Ridge, Perry G., Maxwell, Taylor J., Corcoran, Christopher D., Norton, Maria C., Tschanz, JoAnn T., O’Brien, Elizabeth, Kerber, Richard A., Cawthon, Richard M., Munger, Ronald G., Kauwe, John S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444479/
https://www.ncbi.nlm.nih.gov/pubmed/23028804
http://dx.doi.org/10.1371/journal.pone.0045134