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Mitochondrial Genomic Analysis of Late Onset Alzheimer’s Disease Reveals Protective Haplogroups H6A1A/H6A1B: The Cache County Study on Memory in Aging
BACKGROUND: Alzheimer’s disease (AD) is the most common cause of dementia and AD risk clusters within families. Part of the familial aggregation of AD is accounted for by excess maternal vs. paternal inheritance, a pattern consistent with mitochondrial inheritance. The role of specific mitochondrial...
Autores principales: | Ridge, Perry G., Maxwell, Taylor J., Corcoran, Christopher D., Norton, Maria C., Tschanz, JoAnn T., O’Brien, Elizabeth, Kerber, Richard A., Cawthon, Richard M., Munger, Ronald G., Kauwe, John S. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444479/ https://www.ncbi.nlm.nih.gov/pubmed/23028804 http://dx.doi.org/10.1371/journal.pone.0045134 |
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